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Apellis Pharmaceuticals, Inc. (apls)
| 开盘价:-- |
最高价:-- |
最低价:-- |
52周最高价:-- |
52周最低价:-- |
| 成交量:-- |
平均成交量:-- |
市值:-- |
市盈率:-- |
预期市盈率:-- |
| 每股收益:-- |
贝塔系数:-- |
股息:-- |
收益率:-- |
总股本:-- |
| 机构持股 |
| 持有者 |
持有份额 |
持股比例 |
份额变化 |
变化率 |
报告日期 |
| Fidelity SelectCo, LLC |
1430090 |
1.34% |
-200290 |
-12.28% |
2022-05-31
|
| Wellington Management Company LLP |
14199294 |
13.33% |
1868641 |
15.15% |
2022-03-31
|
| venBio Select Advisor LLC |
9450000 |
8.87% |
894445 |
10.45% |
2022-03-31
|
| Vanguard Group Inc |
8569170 |
8.04% |
652071 |
8.24% |
2022-03-31
|
| T. Rowe Price Associates, Inc. |
7884839 |
7.40% |
2586348 |
48.81% |
2022-03-31
|
| Hartford Funds Management Company, LLC |
7497100 |
7.04% |
23228 |
0.31% |
2022-05-31
|
| BlackRock Inc |
5865712 |
5.51% |
399521 |
7.31% |
2021-12-31
|
| BlackRock Fund Advisors |
3302605 |
3.10% |
-8655 |
-0.26% |
2022-05-31
|
| SSGA Funds Management Inc |
3110404 |
2.92% |
880657 |
39.50% |
2022-05-31
|
| State Street Corporation |
2906456 |
2.73% |
187088 |
6.88% |
2022-03-31
|
| Jennison Associates LLC |
2704390 |
2.54% |
842233 |
45.23% |
2022-03-31
|
| Perceptive Advisors LLC |
1481700 |
1.39% |
-1421700 |
-48.97% |
2022-03-31
|
| Geode Capital Management, LLC |
1493520 |
1.40% |
140691 |
10.40% |
2022-03-31
|
| T. Rowe Price |
1523621 |
1.43% |
876003 |
135.27% |
2022-05-31
|
| PGIM Investments LLC |
1694362 |
1.59% |
-320588 |
-15.91% |
2022-05-31
|
| Delaware Management Company |
2194724 |
2.06% |
500075 |
29.51% |
2022-05-31
|
| Octagon Capital Advisors LP |
2340059 |
2.20% |
319148 |
15.79% |
2022-03-31
|
| EcoR1 Capital, LLC |
5183431 |
4.87% |
1149549 |
28.50% |
2022-03-31
|
| Vanguard Investments Australia Ltd |
2630276 |
2.47% |
19589 |
0.75% |
2022-05-31
|
| RTW INVESTMENTS, LLC |
1990404 |
1.87% |
1990404 |
-- |
2021-12-31
|
| FMR Inc |
1614859 |
1.52% |
-- |
-- |
2021-12-31
|
| JPMorgan Chase & Co |
1587878 |
1.49% |
54736 |
3.57% |
2021-12-31
|
| Morningside Venture Investments Ltd. |
12556342 |
11.80% |
12556342 |
-- |
2020-12-31
|
| Vanguard |
1637128 |
1.68% |
140924 |
9.42% |
2022-01-31
|
| Victory Capital Management Inc. |
1770807 |
1.82% |
114519 |
6.91% |
2021-09-30
|
| Citadel Advisors Llc |
1858432 |
1.91% |
1505416 |
426.44% |
2021-09-30
|
| Logos Global Management LP |
1450000 |
1.49% |
1100000 |
314.29% |
2021-09-30
|
| Hillhouse Capital Advisors, Ltd. |
2929708 |
3.37% |
-1628321 |
-35.72% |
2021-06-30
|
| Baker Bros Advisors LP |
2271917 |
2.61% |
597913 |
35.72% |
2021-06-30
|
| Farallon Capital Management, L.L.C. |
1550000 |
1.78% |
-625000 |
-28.74% |
2021-06-30
|
| Fidelity Management & Research Company LLC |
1674652 |
1.92% |
64293 |
3.99% |
2021-10-31
|
| Cormorant Asset Management, LLC |
1866108 |
2.14% |
-- |
-- |
2021-03-31
|
| Fidelity Management and Research Company |
1620434 |
1.86% |
480708 |
42.18% |
2021-03-31
|
| Goldman Sachs Group Inc |
1331610 |
1.67% |
318550 |
31.44% |
2020-09-30
|
| BlackRock Advisors LLC |
1182893 |
1.49% |
-19224 |
-1.60% |
2021-01-31
|
| Northern Trust Investments Inc |
1119236 |
1.48% |
-65484 |
-5.53% |
2020-12-31
|
| Candriam Luxembourg S.C.A. |
1148865 |
1.52% |
-61533 |
-5.08% |
2020-09-30
|
| Millennium Management LLC |
1075250 |
1.42% |
-282336 |
-20.80% |
2020-06-30
|
| Candriam Belgium |
1148865 |
1.52% |
-46533 |
-3.89% |
2020-10-31
|
| Fidelity International Ltd |
1104349 |
1.73% |
-289936 |
-20.79% |
2020-03-31
|
| BlackRock Advisors (UK) Ltd |
1158232 |
1.82% |
1111489 |
2377.87% |
2019-12-31
|
| Barclays PLC |
1160434 |
1.82% |
1113185 |
2356.00% |
2019-12-31
|
| Boxer Capital LLC |
800000 |
1.26% |
100000 |
14.29% |
2019-12-31
|
| Fidelity Management & Research Company |
732885 |
1.15% |
52805 |
7.76% |
2020-03-31
|
| Fidelity Investments Canada ULC |
683719 |
1.07% |
64647 |
10.44% |
2020-02-29
|
| Orbimed Advisors, LLC |
623859 |
0.98% |
-1199841 |
-65.79% |
2019-09-30
|
| Fiduciary Trust Co |
705923 |
1.11% |
1675 |
0.24% |
2019-09-30
|
| Sectoral Asset Management Inc |
996983 |
1.57% |
-492974 |
-33.09% |
2019-09-30
|
| Hillhouse Capital Management, Ltd. |
2098581 |
3.29% |
-- |
-- |
2019-06-30
|
| Morgan Stanley - Brokerage Accounts |
1248394 |
1.96% |
1191729 |
2103.11% |
2019-03-31
|
| Fundlogic SAS |
731494 |
1.15% |
731494 |
-- |
2019-03-31
|
| Westfield Capital Management Company, LP |
731451 |
1.16% |
-36425 |
-4.74% |
2019-03-31
|
| BlackRock Asset Management Canada Ltd |
826763 |
1.31% |
-177 |
-0.02% |
2019-05-31
|
| Vivo Capital, LLC |
874573 |
1.55% |
-479981 |
-35.43% |
2018-12-31
|
| Clough Capital Partners, LP |
562734 |
1.00% |
-26382 |
-4.48% |
2018-12-31
|
| Candriam Luxembourg |
527700 |
0.94% |
12000 |
2.33% |
2018-12-31
|
| Adage Capital Partners Gp LLC |
500000 |
0.89% |
281000 |
128.31% |
2018-12-31
|
| Sofinnova Ventures |
549580 |
0.98% |
-682024 |
-55.38% |
2018-09-30
|
| RA Capital Management, LLC |
900000 |
1.60% |
-- |
-- |
2018-09-30
|
| BlackRock Institutional Trust Company NA |
973912 |
1.73% |
753068 |
341.00% |
2018-06-30
|
| Morningside Venture (VI) Investments Ltd |
11353303 |
22.56% |
11353303 |
-- |
2017-12-31
|
| State Street Corp |
1208204 |
2.15% |
1037258 |
606.78% |
2018-06-30
|
| Northern Trust Investments N A |
405435 |
0.72% |
285992 |
239.44% |
2018-06-30
|
| RS Investment Management Co. LLC |
519273 |
0.92% |
372603 |
254.04% |
2018-06-30
|
| Opaleye Management Inc |
265000 |
0.47% |
265000 |
-- |
2018-06-30
|
| NF Trinity Capital (Hong Kong) Ltd |
357142 |
0.64% |
-- |
-- |
2018-06-30
|
| Harbor Capital Advisors Inc |
224871 |
0.40% |
224871 |
-- |
2018-06-30
|
| Prudential Investments LLC |
368569 |
0.66% |
-- |
-- |
2018-05-31
|
| NORGES BANK |
75000 |
0.15% |
75000 |
-- |
2017-12-31
|
| Deerfield Management Co |
513000 |
1.02% |
513000 |
-- |
2017-12-31
|
| AllianceBernstein LP |
85000 |
0.17% |
85000 |
-- |
2017-12-31
|
| Oxford Asset Management, LLC |
51670 |
0.10% |
51670 |
-- |
2017-12-31
|
| Northern Trust Asset Management |
26230 |
0.05% |
164 |
0.63% |
2018-01-31
|
| Deutsche Bank AG |
20620 |
0.04% |
20620 |
-- |
2017-12-31
|
| Russell Investment Management Co |
27395 |
0.05% |
27395 |
-- |
2018-01-31
|
| Charles Schwab Investment Management Inc |
39742 |
0.08% |
39742 |
-- |
2017-12-31
|
| BlackRock Investment Management, LLC |
139720 |
0.36% |
139720 |
-- |
2017-11-30
|
| Pacific Life Fund Advisors LLC (PLFA) |
21023 |
0.04% |
-- |
-- |
2018-02-28
|
| OPERS |
17413 |
0.03% |
17413 |
-- |
2017-12-31
|
| Morgan Stanley & Co Inc |
18908 |
0.04% |
18908 |
-- |
2017-12-31
|
| California State Teachers Retirement Sys |
17066 |
0.03% |
17066 |
-- |
2017-12-31
|
| FMG LLC |
22235 |
0.04% |
-97 |
-0.43% |
2018-01-31
|
| TIAA-CREF Investment Management LLC |
15829 |
0.03% |
15829 |
-- |
2017-12-31
|
| Teachers Advisors Inc |
12435 |
0.02% |
12435 |
-- |
2017-12-31
|
| K2/D&S Management Co LLC |
16069 |
0.03% |
-2936 |
-15.45% |
2018-01-31
|
| John Hancock Investment Mgt Svcs, LLC |
5755 |
0.01% |
5755 |
-- |
2017-12-31
|
| Variable Annuity Life Insurance Co |
6365 |
0.01% |
6365 |
-- |
2017-12-31
|
| Lincoln Investment Advisors Corporation |
10500 |
0.02% |
10500 |
-- |
2017-12-31
|
| Thrivent Financial For Lutherans |
8471 |
0.02% |
8471 |
-- |
2017-11-30
|
| Nationwide Fund Advisors |
5547 |
0.01% |
5547 |
-- |
2017-12-31
|
| Vanguard Group Inc. |
3911 |
0.01% |
3400 |
665.36% |
2017-12-31
|
| BlackRock |
5029 |
0.01% |
5029 |
-- |
2017-12-31
|
| SPGP |
13793 |
0.04% |
13793 |
-- |
2017-11-30
|
| Deutsche Asset & Wealth Management Investment GmbH |
3373 |
0.01% |
-- |
-- |
2018-01-30
|
| MML Investment Advisers, LLC |
1498 |
-- |
1498 |
-- |
2017-12-31
|
| ProShare Advisors LLC |
1569 |
-- |
1569 |
-- |
2017-12-31
|
| Invesco PowerShares Capital Mgmt LLC |
563 |
-- |
-- |
-- |
2018-01-18
|
| GE Asset Management Inc |
200 |
-- |
200 |
-- |
2017-12-31
|
| 共同基金持股 |
| 持有者 |
持有份额 |
持股比例 |
份额变化 |
变化率 |
报告日期 |
| iShares Russell 2000 Growth ETF |
673736 |
0.63% |
-776 |
-0.12% |
2022-05-31
|
| Wellington Global Health Care Equity |
639395 |
0.60% |
-127175 |
-16.59% |
2022-04-30
|
| T. Rowe Price Small-Cap Value Fund |
632469 |
0.59% |
430769 |
213.57% |
2022-03-31
|
| Vanguard Health Care Fund |
3791661 |
3.56% |
921282 |
32.10% |
2022-03-31
|
| Vanguard Total Stock Market Index Fund |
2616157 |
2.46% |
19971 |
0.77% |
2022-05-31
|
| Hartford MidCap Fund |
2329182 |
2.19% |
-614576 |
-20.88% |
2022-04-30
|
| Vanguard Small Cap Index |
2243702 |
2.11% |
633 |
0.03% |
2022-05-31
|
| iShares Russell 2000 ETF |
1751614 |
1.64% |
2970 |
0.17% |
2022-05-31
|
| SPDR |
1517441 |
1.42% |
51290 |
3.50% |
2022-05-31
|
| T. Rowe Price New Horizons Fund |
1405164 |
1.32% |
69299 |
5.19% |
2022-03-31
|
| Vanguard Small Cap Growth Index Fund |
1370907 |
1.29% |
18001 |
1.33% |
2022-05-31
|
| Fidelity |
1363284 |
1.28% |
-- |
-- |
2022-04-30
|
| T. Rowe Price Health Sciences Fund |
1283704 |
1.21% |
52483 |
4.26% |
2022-03-31
|
| Vanguard Extended Market Index Fund |
1173329 |
1.10% |
1139 |
0.10% |
2022-05-31
|
| Delaware Small Cap Core Fund |
1140684 |
1.07% |
63693 |
5.91% |
2022-04-30
|
| Vanguard Explorer Fund |
1090757 |
1.02% |
42112 |
4.02% |
2022-03-31
|
| Macquarie US Small Cap Core Equity |
1076991 |
1.01% |
31100 |
2.97% |
2022-03-31
|
| T. Rowe Price Small-Cap Stock Fund |
973276 |
0.91% |
364544 |
59.89% |
2022-03-31
|
| PGIM Jennison Health Sciences Fund |
874631 |
0.82% |
-276799 |
-24.04% |
2022-05-31
|
| iShares Biotechnology ETF |
681206 |
0.64% |
-9339 |
-1.35% |
2022-05-31
|
| JPMorgan Small Cap Growth Fund |
535347 |
0.50% |
-4151 |
-0.77% |
2022-02-28
|
| Victory RS Small Cap Growth CIT |
549350 |
0.52% |
-71890 |
-11.57% |
2021-12-31
|
| Victory RS Small Cap Growth Fund |
549350 |
0.52% |
-71890 |
-11.57% |
2021-12-31
|
| Candriam Eqs L Biotechnology |
694425 |
0.71% |
-- |
-- |
2022-01-31
|
| Rhenman Healthcare Eq L/S |
561269 |
0.58% |
381269 |
211.82% |
2021-09-30
|
| Hartford MidCap HLS Fund |
522431 |
0.60% |
61795 |
13.42% |
2021-10-31
|
| Invesco Discovery Fund |
438646 |
0.51% |
-- |
-- |
2021-03-31
|
| Invesco OFI Small Cap Growth |
438646 |
0.51% |
-- |
-- |
2021-03-31
|
| iShares Nasdaq Biotechnology ETF |
682217 |
0.85% |
-3072 |
-0.45% |
2021-05-28
|
| Fidelity Global Innovators Cl |
746983 |
0.93% |
-1091 |
-0.15% |
2020-06-30
|
| OFI Global Small Cap Growth |
432054 |
0.57% |
26127 |
6.44% |
2020-09-30
|
| Vanguard Mid Cap Growth |
417090 |
0.65% |
196310 |
88.92% |
2020-06-30
|
| Invesco Oppenheimer Discovery Fund |
405927 |
0.64% |
120169 |
42.05% |
2020-06-30
|
| Fidelity Special Situations Fund |
451664 |
0.71% |
-- |
-- |
2020-03-31
|
| BlackRock Health Sciences Opps Port |
394304 |
0.62% |
-- |
-- |
2020-05-31
|
| HBM Healthcare Investments AG |
300000 |
0.47% |
-140000 |
-31.82% |
2020-03-31
|
| Hartford Healthcare Fund |
297220 |
0.47% |
-2560 |
-0.85% |
2020-03-31
|
| USAA Science & Technology Fund |
438460 |
0.69% |
53360 |
13.86% |
2019-12-31
|
| Hartford Small Cap Growth HLS Fund |
280863 |
0.44% |
-11818 |
-4.04% |
2019-12-31
|
| Biotech Growth Trust Plc |
602400 |
0.95% |
-220000 |
-26.75% |
2019-08-31
|
| Variopartner Sectoral Biotech Opps Fd |
357860 |
0.56% |
-- |
-- |
2019-07-31
|
| MEDICAL BioHealth |
262728 |
0.41% |
-32000 |
-10.86% |
2019-06-30
|
| Hartford Small Cap Growth Fund |
242759 |
0.38% |
-- |
-- |
2019-07-31
|
| Harbor Small Cap Growth Fund |
296141 |
0.47% |
-11180 |
-3.64% |
2019-03-31
|
| Westfield Capital Mgt Sm-Cap Gr Eq-UBS |
296141 |
0.47% |
-11180 |
-3.64% |
2019-03-31
|
| iShares US Small Cap ETF (CAD-Hedged) |
732159 |
1.16% |
-1233 |
-0.17% |
2019-05-30
|
| AST Small Cap Growth Opportunities Port |
237170 |
0.38% |
106630 |
81.68% |
2019-03-31
|
| Clough Global Opportunities |
214401 |
0.34% |
-- |
-- |
2019-02-28
|
| JNL Multi-Manager Small Cap Growth Fund |
157230 |
0.28% |
5380 |
3.54% |
2018-12-31
|
| Rs Investments Custom Growth |
157230 |
0.28% |
5380 |
3.54% |
2018-12-31
|
| State Street Russell Small Cap |
149300 |
0.27% |
2800 |
1.91% |
2019-02-28
|
| State Street Russell Small/Mid Cap |
146097 |
0.26% |
6097 |
4.35% |
2019-02-28
|
| ZIL Blackrock Global Fds Wld Health Sci |
137429 |
0.24% |
-- |
-- |
2018-11-30
|
| ALPS Medical Breakthroughs ETF |
131488 |
0.23% |
-- |
-- |
2019-02-28
|
| Victory RS Science and Technology Fund |
117793 |
0.21% |
-4690 |
-3.83% |
2018-12-31
|
| ZIL Blackrock Glbl Wrd Healthscience USD |
137429 |
0.24% |
-- |
-- |
2018-11-30
|
| FCP MEDICAL BioHealth-Trends |
178401 |
0.32% |
-- |
-- |
2018-10-31
|
| APO Medical Opportunities |
117249 |
0.21% |
41881 |
55.57% |
2018-12-31
|
| BGF World Healthscience Fund |
137429 |
0.24% |
-- |
-- |
2018-09-30
|
| Clough Global Equity |
97397 |
0.17% |
-- |
-- |
2018-10-31
|
| Schwab US Small-Cap ETF |
93797 |
0.17% |
126 |
0.13% |
2018-11-21
|
| Vanguard Total Stock Mkt Idx |
635793 |
1.13% |
-- |
-- |
2018-07-31
|
| Vanguard Extended Market Idx Inv |
457920 |
0.82% |
-- |
-- |
2018-07-31
|
| RS Small Cap Growth A |
382270 |
0.68% |
382270 |
-- |
2018-06-30
|
| Prudential Jennison Health Sciences A |
368569 |
0.66% |
-- |
-- |
2018-07-31
|
| iShares Russell 2000 Growth |
344127 |
0.59% |
-332 |
-0.10% |
2018-09-12
|
| Fidelity Advisor |
327401 |
0.58% |
-70988 |
-17.82% |
2018-07-31
|
| Harbor Small Cap Growth Instl |
224871 |
0.40% |
224871 |
-- |
2018-06-30
|
| BlackRock Health Sciences Opps Inv A |
266504 |
0.47% |
-- |
-- |
2018-07-31
|
| Fidelity Spartan |
161010 |
0.29% |
-- |
-- |
2018-07-31
|
| RS Technology A |
122483 |
0.22% |
-24187 |
-16.49% |
2018-06-30
|
| JNL Multi-Manager Small Cap Growth B |
91150 |
0.16% |
91150 |
-- |
2018-06-30
|
| Northern Trust Russell 2000 Index Fund - DC - Non-Lending |
88615 |
0.16% |
-212 |
-0.24% |
2018-07-31
|
| BlackRock Extended Equity Market K |
59673 |
0.11% |
47995 |
410.99% |
2018-06-30
|
| AST Small Cap Growth Opportunities |
69170 |
0.12% |
-180 |
-0.26% |
2018-07-31
|
| CREF Stock R1 |
88558 |
0.16% |
72979 |
468.44% |
2018-06-30
|
| Schwab Small Cap Index |
67300 |
0.12% |
45800 |
213.02% |
2018-06-30
|
| The Vanguard Russell 2000 Growth Index |
63907 |
0.11% |
50527 |
377.63% |
2018-06-30
|
| BlackRock Russell 2000 |
51073 |
0.09% |
33495 |
190.55% |
2018-06-30
|
| BlackRock Russell 2500 |
49730 |
0.09% |
36994 |
290.47% |
2018-06-30
|
| BioShares |
36223 |
0.06% |
-- |
-- |
2018-07-03
|
| Vanguard Health Care ETF |
36530 |
0.07% |
36530 |
-- |
2018-05-31
|
| VALIC Company I Small Cap Agrsv Gr |
29300 |
0.05% |
29300 |
-- |
2018-04-30
|
| iShares Russell 2000 Value |
31149 |
0.06% |
-51 |
-0.16% |
2018-06-21
|
| Russell US Small Cap Equity I |
27395 |
0.05% |
-- |
-- |
2018-04-30
|
| iShares Micro-Cap |
26209 |
0.05% |
-- |
-- |
2018-06-14
|
| Vanguard Instl Ttl Stk Mkt Idx InstlPls |
21680 |
0.04% |
10000 |
85.62% |
2018-04-30
|
| Pacific Select Health Sciences I |
16849 |
0.03% |
-- |
-- |
2018-04-30
|
| Schwab US Broad Market ETF |
19340 |
0.04% |
40 |
0.21% |
2018-05-17
|
| AXA 2000 Managed Volatility K |
15225 |
0.03% |
-- |
-- |
2018-02-28
|
| Franklin K2 Alternative Strategies A |
11304 |
0.02% |
11304 |
-- |
2017-12-31
|
| TIAA-CREF Small-Cap Blend Idx Inst |
12435 |
0.02% |
12435 |
-- |
2017-12-31
|
| Vanguard Russell 2000 ETF |
9830 |
0.02% |
7763 |
375.57% |
2017-12-31
|
| Master Small Cap Index |
6649 |
0.01% |
6649 |
-- |
2017-12-31
|
| Northern Small Cap Index |
6447 |
0.01% |
6447 |
-- |
2017-12-31
|
| iShares Russell 3000 |
6480 |
0.01% |
-42 |
-0.64% |
2018-01-24
|
| Vanguard Russell 2000 Growth ETF |
4872 |
0.01% |
3894 |
398.16% |
2017-12-31
|
| Pacific Select Small-Cap Index I |
4174 |
0.01% |
4174 |
-- |
2017-12-31
|
| Vanguard Balanced Index Inv |
1956 |
0.01% |
1956 |
-- |
2017-11-30
|
| ProShares Ultra Russell2000 |
914 |
-- |
914 |
-- |
2017-12-31
|
